Cumbria Police responded to a road traffic collision in Denton Street in Carlisle.
Received at 3.48am this morning September 23, the collision involved an Audi car and a pedestrian a local man in his 20s.
Emergency services attended, however the pedestrian died at the scene.
A road closure remains in place whilst police continue with their enquiries.
Anyone who witnessed what occurred or the moments leading up to it is urged to contact police.
Officers are particularly keen to hear from two cyclists in the area shortly before the collision who may be able to assist, or from anyone who saw these cyclists.
Anyone with information relating to this incident can report online at www.cumbria.police.uk/reportit quoting incident number 28 of 23 September.
You can also phone on 101.
Alternatively you can contact Crimestoppers, anonymously, on 0800 555 111.